(1991). Life as emergence: The roots of a new paradigm in theoretical biology. World Futures: Vol. 32, Creative Evolution in Nature, Mind, and Society, pp. 133-149.

Firstly we consider the new results about enzymatic capabilities in the RNA. In this framework we analyse the sequence-folding duality as a precursor of the genotype/phenotype duality. We discuss then which are the evolutive potentialities and limitations for a system with the absence and the presence of a nucleic acid to proteins translator code. We study the arise of the code in the living systems as a form of deep interlooking between the logic of the machinery and its hardware, discussing (...) some problems that abstract modelization of this process implies. Finaly we propose to redefine the informational vocabulary usually employed in Molecular Biology. (shrink)

We study the appearance of genetic information starting from a system where self-reproductive and enzymatic functions are supported by the same sort of molecules. In a first phase, the information must have arisen in the form of rate independent sequences as records of enzymatic functions. Although this stage must have played an important role in evolution, it will be shown how its evolutive capacities were blocked by the impossibility of appearance of geno/phenotype duality. Finally, a logical scheme is proposed for (...) a transition process toward a system with a code offering a simplification of the conditions required from the assumption of a maximum use of the double RNA capacity, both reproductive and enzymatic. (shrink)

Este estudio tiene como objetivo identificar la tipología y los patrones de los mensajes desinformativos relacionados con la salud y la nutrición que se difundieron durante la primera etapa de la pandemia COVID-19 (marzo-noviembre de 2020). Para ello, se realizó un estudio cuantitativo exploratorio con dos tipos de datos. Los primeros provienen del estudio de 95 documentos (artículos científicos) hallados en la base de datos SCOPUS a través de búsquedas booleanas con los términos desinformación, engaño, salud y nutrición. A estos (...) documentos se les aplicó un formulario de registro, indicando los siguientes ítems: a) el tema del artículo (salud o nutrición); b) el tipo de mensaje erróneo (desinformación o engaño); c) el país en el que se realizó el estudio; d) el tipo de participantes (público general, jóvenes, ancianos, profesionales de la salud, estudiantes universitarios); y e) el tipo de canal de información estudiado (Twitter, Facebook, YouTube, Instagram, periódicos impresos, periódicos digitales, plataformas web, televisión, entre otros). Por otro lado, se seleccionaron 95 ingredientes o alimentos que fueron diseminados vía WhatsApp en diferentes bulos en español durante el primer mes de confinamiento (marzo-abril de 2020). Se aplicó un formulario para evaluar el contenido de los engaños, identificando: a) el tipo de sustancia o alimento (fruta, verdura, legumbre, nuez, hierba, entre otros); y b) las fuentes de información a las que se refirió el engaño (autoridades sanitarias, público general, organismos médicos, entre otros). Finalmente, los resultados de ambos estudios cuantitativos concluyeron que el patrón internacional de difusión de bulos fue principalmente sobre la salud en general, y que la desinformación sobre nutrición fue minoritaria, y en el 91% de los casos estuvo relacionada con la ingesta de frutas y verduras, afirmando que podrían prevenir o curar la COVID-19, sin ninguna evidencia científica. (shrink)

t. 1. Introducción a la filosofía del derecho.

Firstly we consider the new results about enzymatic capabilities in the RNA. In this framework we analyse the sequence-folding duality as a precursor of the genotype/phenotype duality. We discuss then which are the evolutive potentialities and limitations for a system with the absence and the presence of a nucleic acid to proteins translator code. We study the arise of the code in the living systems as a form of deep interlooking between the logic of the machinery and its hardware, discussing (...) some problems that abstract modelization of this process implies. Finaly we propose to redefine the informational vocabulary usually employed in Molecular Biology. (shrink)

La infección por el virus del papiloma humano (VPH) constituye la causa necesaria, aunque no suficiente, de la enfermedad de transmisión sexual más frecuente en el mundo, responsable del 4,5 % de todos los cánceres en ambos sexos. La vacunación frente al VPH, con niveles de eficacia y seguridad similares en ambos sexos, está dirigida básicamente a mujeres, para reducir la incidencia de infección y sus consecuencias, como el cáncer de cérvix. La transmisibilidad del virus en ambos sexos y la (...) inmunidad colectiva que proporciona la vacunación universal hace que su extensión al sexo masculino constituya una cuestión no solo de salud pública, sino también un dilema bioético relacionado con la protección de la salud y la equitativa distribución de los recursos. Este trabajo aborda el análisis bioético de la extensión de la vacunación contra VPH a ambos sexos. (shrink)

¿El conflicto armado ha transformado los roles de la mujer en Colombia? En este artículo se quiere evaluar la diversidad de escenarios y roles que las mujeres adquirieron durante el conflicto armado en Colombia. Para dirigir el rumbo de esta investigación y la posibilidad de evaluar alguno escenarios de posacuerdo, este texto se propone: realizar una consideración epistemológica por parte del feminismo latinoamericano que tenga en cuenta la pluralidad de relatos violentos en Latinoamérica analizar relatos de mujeres partícipes en la (...) guerra que permitan evaluar el rol de la mujer más allá de su simple victimización; examinar la situación de la mujer dentro de los conflictos bélicos colombianos y presentar cómo se diferencia de las situaciones de guerra ocurridas en Europa. Todos estos puntos permiten evaluar cómo la guerra en Colombia ha sido fundamental para contemplar los roles de las mujeres más allá del de víctima, como, por ejemplo, las mujeres activistas que han participado en la reconciliación y el ejercicio de memoria histórica durante el acuerdo de paz y el posacuerdo. Dicho logro promueve un porvenir del feminismo que abre nuevos espacios de acción para la mujer, los cuales, debido a la limitación de este trabajo, quedan aún por explorar. (shrink)

Ciencias sociales : saberes coloniales y eurocéntricos / Edgardo Lander / - Europa modernidad y eurocentrismo / Enrique Dussel / - La colonialidad a lo largo y a lo ancho : el hemisferio occidental en el horizonte colonial de la modernidad / Walter D. Mignolo / - Naturaleza del poscolonialismo : del eurocentrismo al globocentrismo / Fernando Coronil / - El lugar de la naturaleza y la naturaleza del lugar : ¿globalización o postdesarrollo? / Arturo Escobar / - Ciencias sociales, (...) violencia epistémica y el problema de la invención del otro / Santiago Castro-Gómez / - Superar la exclusión, conquistar la equidad : reformas, políticas y capacidades en el ámbito social / Alejandro Moreno / - Abrir, impensar, y redimesionar las ciencias sociales en América Latina y el Caribe. ¿Es posible una ciencia social no eurocéntrica en nuestra región? / Francisco López Segrera / - Colonialidad del poder, eurocentrismo y América Latina / Aníbal Quijano. (shrink)

If Unamuno had been able to choose how to be remembered, he would have wanted him to be a poet. This book wants to do justice to that happy possibility. But above all because Unamuno was a poet in the highest sense: he was while writing the same essay as a novel, or theater, letter or verse, and he was also a poet when he passionately lived all the facets of his intense existence. His intellectual work was poetic and his (...) personal relationships, as well as his political activity, also responded to that peculiar Unamunian aesthetic in which the vital horizon is inescapably confused with the tasks of thought." --Translated from back cover. (shrink)

Artículos Venezuela, ¿un estado de derecho? Venezuela. A state of rule of law? Belandria, Margarita Una aproximación al léxico del crimen y la pasión en Medea y Phaedra de Séneca. An approach to the speech of crime and passion in Seneca’s Medea and Phaedra.de Brand, Isabel Relación entre la iglesia y las fuerzas armadas. Relation between church and armed forces. González G., George Sobre el arte diabólico de la tortura. Regarding the diabolical art of torture. Márquez Rodríguez, Alexis Hermenéutica crítica (...) de la historia del tiempo presente: la invención de la tradición en la 'revolución bolivariana'. Critical hermeneutics of present time history: the invention of tradition in 'bolivarian revolution'. Mora García, José Pascual En torno al principio del «iura novit curia». Concerning the «iura novit curia» principle. Quintero Moreno, Rafael Experiencia del conocimiento. Experience of knowledge. Ramis Muscato, Pompeyo La doctrina platónica del alma en el diálogo el Fedón. The platonic doctrine of the Fedon’s soul. Suzzarini, Andrés Importancia jurídica de valorar el daño a la persona. Legal importance to value the damage to the person. Vielma Mendoza, Yoleida Interdisciplinares Psicopatologías en la Grecia antigua a través de sus mitos. Psychopathology in ancient Greece through myths. López Saco, Julio Recensiones 'Los juristas del horror', de Ingo Müller. Angola Heredia, José Tomás Informaciones Índice acumulado. (shrink)

Jakob Johannes von Uexküll’s biological thought influenced a new path to approach the view of a living being throughout of the twentieth century. At the beginning of the past century, in Spain a “new vertebrate way of thinking” was generated, as Ortega would say. And the work of Uexküll initiated an interest in the circles of thinkers of the likes of Julio Caro Baroja, José Ortega y Gasset, and Xavier Zubiri among others. My aim is describing how Uexküll plays (...) a part in the development in the foundations of thoughts of these thinkers; in particular, Ortega and Zubiri’s thought and their interactions between the circumstantiality and formality, respectively, and Uexküll’s Umwelt. In fact, Ortega’s biological thought was the foundation of his vitalism realism and made a giant step in philosophical anthropology existentialism in his Meditations of Quixote in 1911. We will also see the anthropologist Caro Baroja’s epistemic Uexküll influences. A retrospective view of Spanish thought will be developed, where the seeds of Uexküll made fruitful the development of several authors, as well as some transitive or indirect influences; even the generation of discrepancies in others. Finally, we will describe the development, in Spanish, that had the work of Thure von Uexküll, which includes the work of his father. With Thure, the Uexküll influences in Spain concluded until the start of interest in zoosemiotics and biosemiotics. (shrink)

En el presente artículo se analiza el cuento “La muerte de la acacia” de la escritora colombiana Marvel Moreno desde una perspectiva pluridisciplinaria que integra elementos de la teoría literaria, la hermenéutica, la sociología y los estudios de género. Con el objetivo de ir más allá de la anécdota narrada e indagar en los temas propuestos por el cuento, se estudia la particular estructuración de la voz narrativa, que revela la organización de la sociedad barranquillera de principios del siglo (...) xx, en la que la violencia contra la mujer está presente pero aparece de manera velada. Se examinan, asimismo, las estrategias a las que recurre el personaje femenino central para burlar el sistema de vigilancia y disciplina que se le impone y las consecuencias que esto le acarrea. (shrink)

Resumen Debido a la polisemia que la complejidad exhibe, se pretenden exponer las distintas posturas, definiciones, descripciones y debates acerca de esta, a la luz de lo descrito por Carlos Maldonado, Edgar Morin, Ilya Progogine, Murray Gell-Mann, Leonardo Rodríguez y Julio Aguirre, quienes comportan un principio dialógico y translúcido, que integraría la lógica clásica teniendo en cuenta sus límites de facto y de jure, que además llevaría en sí el principio de la Unitas Multiplex, que escapa a la unidad (...) abstracta por lo alto y por lo bajo. Luego de la presentación de las posturas de los autores mencionados se pasa a describir los encuentros y desencuentros que de estos aparecen sobre este concepto; y finalizar al proponer una definición y caracterización personal de la complejidad.Due to the polysemy of Complexity, it is intended to expose different postures, definitions, descriptions and debates about It, in the light of what was described by Carlos Maldonado, Edgar Morin, Ilya Prigogine, Murray Gell-Mann, Leonardo Rodríguez and Julio Aguirre. For them it implies a dialogical and translucent principle that would integrate classical logic considering its de facto and de jure limits, and that in addition would take in himself the principle of Unitas Multiplex that escapes to the abstract unity by the high and by the low. After the presentation of the positions of the mentioned authors the paper goes on to describe encounters and disagreements about this concept finally proposing a definition and characterization of complexity. (shrink)

Resumen Debido a la polisemia que la complejidad exhibe, se pretenden exponer las distintas posturas, definiciones, descripciones y debates acerca de esta, a la luz de lo descrito por Carlos Maldonado, Edgar Morin, Ilya Progogine, Murray Gell-Mann, Leonardo Rodríguez y Julio Aguirre, quienes comportan un principio dialógico y translúcido, que integraría la lógica clásica teniendo en cuenta sus límites de facto y de jure, que además llevaría en sí el principio de la Unitas Multiplex, que escapa a la unidad (...) abstracta por lo alto y por lo bajo. Luego de la presentación de las posturas de los autores mencionados se pasa a describir los encuentros y desencuentros que de estos aparecen sobre este concepto; y finalizar al proponer una definición y caracterización personal de la complejidad.Due to the polysemy of Complexity, it is intended to expose different postures, definitions, descriptions and debates about It, in the light of what was described by Carlos Maldonado, Edgar Morin, Ilya Prigogine, Murray Gell-Mann, Leonardo Rodríguez and Julio Aguirre. For them it implies a dialogical and translucent principle that would integrate classical logic considering its de facto and de jure limits, and that in addition would take in himself the principle of Unitas Multiplex that escapes to the abstract unity by the high and by the low. After the presentation of the positions of the mentioned authors the paper goes on to describe encounters and disagreements about this concept finally proposing a definition and characterization of complexity. (shrink)

Timely and provocative essays on bioethical questions brought to the forefront by the bioterrorist threat.

This article gives a conceptual review of the e-value, ev(H|X) – the epistemic value of hypothesis H given observations X. This statistical significance measure was developed in order to allow logically coherent and consistent tests of hypotheses, including sharp or precise hypotheses, via the Full Bayesian Significance Test (FBST). Arguments of analysis allow a full characterization of this statistical test by its logical or compositional properties, showing a mutual complementarity between results of mathematical statistics and the logical desiderata lying at (...) the foundations of this theory. (shrink)

El propósito de este libro es de examinar cuales fueron los órdenes epistemológicos, las prácticas discursivas y los mecanismos disciplinarios que hicieron posible en el siglo XX la construcción de un objeto de conocimiento llamado "Latinoamérica", y de una serie de saberes filosóficos sobre "lo latinoamericano". El autor realiza un ejercicio deconstructivo de aquellas narrativas que, con base a la creación de identidades homogéneas, buscaron presentar a Latinoamérica como lo "otro" de la modernidad occidental, e incluso como el continente llamado (...) a mostrar un camino nuevo de liberación para toda la humanidad. A través de un diálogo con pensadores como Foucault, Said, Rama, Lyotard, Mignolo y Spivak, el autor muestra que los principales temas, registros y motivos esgrimidos a favor de una "exterioridad" latinoamericana con respecto a la modernidad, son en realidad discursos pertenecientes a un orden moderno del saber. (shrink)

In this paper, we analyze the legal situation regarding physician-assisted suicide in the world. Our hypothesis is that the prohibitive stance on physician-assisted suicide in most societies in the world today seems to be related to our moral attitudes toward suicide. This brings us to a discussion about life itself. We claim that the total lack of legal protection for physician-assisted suicide from international organizations and most countries in the world lies in a philosophical assumption that supports much of our (...) common beliefs about what life really is. This assumption states that life must be thought of as not belonging exclusively to the individual. We argue that this assumption is a misconception that can be heard in the debate on suicide. Consequently we endorse a different conception of life which tends to favor a pro-choice stance towards suicide and assisted death in general. This position takes the patient’s decision about when to die more seriously. We conclude that there is no reason why physician-assisted suicide does not deserve legal protection as an individual right to die under international law. (shrink)

Johann Gottfried Herder, like his contemporaries, reflected on language and in 1772 published the Treatise on the Origin of Language, which in the previous year had earned the distinction of the Berlin Academy for best essay. However, even today, much of his thought is unknown, ignoring the fact that some of the modern approaches of contemporary philosophy, philosophical anthropology or even sociobiology are already stated there, namely in the narratives resulting from the enunciation of the four natural laws. More than (...) justifying the origin of language, the philosopher’s essay also allows us to understand human nature, inserting its genesis at the heart of philosophical anthropology and contradicting, if not even confronting in this way, the divine tradition of this attribution. Thus, at first, a generic analysis of the work will be carried out, highlighting the fundamental theses that will allow the establishment of a dialogue with some of the contemporary philosophical approaches. Then, admitting the possibility of a scenario of technological singularity, as stated by Irving John Good, Vernor Vinge or Ray Kurzweil, to verify the plausibility and validity of Herder’s theses regarding the scope of language and human nature and how this could constitute a frontier of resistance. (shrink)

El filósofo mexicano Emilio Uranga (1921-1988) es recordado por su Análisis del ser del mexicano (1952) y por su labor como periodista político y asesor de López Mateos, Díaz Ordaz, Echeverría y López Portillo. Es posible tender un puente entre los dos aspectos, gracias a su concepción ontologizante de la Revolución Mexicana, leitmotiv de su producción teórica.

The first form of the inside-outside dichotomy appears as a self-encapsulated system with an active border. These systems are based on two complementary but asymmetric processes: constructive and interactive. The former physically constitute the system as a recursive network of component production, defining an inside. The maintenance of the constructive processes implies that the internal organization also constrains certain flows of matter and energy across the border of the system, generating interactive processes. These interactive processes ensure the maintenance of the (...) constructive processes thus specifying a meaningful outside. Upon this basic form of identity formation, the evolutionary and historical domain is open for the emergence of a whole hierarchy and ecology of insides and outsides. These which mutually subsume and collaborate in the maintenance of the essential inside-outside dichotomy that defines the conditions of possibility of the subjects and the worlds they generate. (shrink)

Recent research in philosophy of science has shown that scientists rely on a plurality of strategies to develop successful explanations of different types of phenomena. In the case of biology, most of these strategies go far beyond the traditional and reductionistic models of scientific explanation that have proven so successful in the fundamental sciences. Concretely, in the last two decades, philosophers of science have discovered the existence of at least two different types of scientific explanation at work in the biological (...) sciences, namely: mechanistic and structural explanations. Despite the growing evidence about the radically different nature of these two types of explanation, no inquiry has been conducted to date to determine the ontological reasons that might underlie these differences, nor the way in which these types of explanations can be systematically related with each other. Here, we aim to cover this gap by connecting this plurality of research strategies with the existence of emergent levels of reality. We argue that the existence of these different—and apparently incompatible—explanatory strategies to account for biological phenomena derives from the existence of “ontological jumps” in nature, which generate different regimes of causation that in turn demand the development of different explanatory frameworks. We identify two of these strategies—mechanistic modelling and network modelling—and connect them to the existence of two ontological regimes of causation. Finally, we relate them with each other in a systematic way. In this vein, our paper provides an ontological justification for the plurality of explanatory strategies that we see in the life sciences. (shrink)

We show how the Full Bayesian Significance Test (FBST) can be used as a model selection criterion. The FBST was presented by Pereira and Stern as a coherent Bayesian significance test. Key Words: Bayesian test; Evidence; Global optimization; Information; Model selection; Numerical integration; Posterior density; Precise hypothesis; Regularization. AMS: 62A15; 62F15; 62H15.

This paper develops a largely neglected parallel between prudence and population ethics. Prudence is generally understood to be concerned with the balancing of well-being over time. How, precisely, well-being ought to be balanced over time, however, is a fervently debated question. I argue that developing a standard guiding such evaluations is exceedingly challenging. This is due to an often overlooked fact about prudence, namely that it shares a structural similarity with population ethics: In both contexts, we assess the comparative value (...) of populations of personstages/people, which may vary in number and level of well-being. Based on this analogy, I show that the development of an adequate theory of prudence runs into very similar impossibility results as obtain in population ethics. In particular, I prove that Arrhenius’ fifth impossibility theorem can be applied to prudence. I develop and compare four possible answers to this challenge. First, I discuss the possibility of accepting the very repugnant conclusion intrapersonally. Second, I present and further develop Donald Bruckner’s Minimax Regret approach, which gives up Transitivity. Third, I apply Jacob Nebel’s Lexical Threshold View to prudence and critically evaluate it. Lastly, I introduce what I call the Negative Lexicality View, which is based on Lexical Threshold View but overcomes some of its problems. (shrink)